Hoffman had to go, regardless. Marlee Hammond said "If only you knew how unsurprising this is" which implies that Caryk was *not* liked in the wives' room. Julie Turris also chimed in, supporting this. Wouldn't be a stretch to assume that at least some of them (wives) believe Caryk did this (as in not even doubting it); reasonable to believe that at least some players feel the same (certainly Karlsson does).
Ok, Hoffman is gone. But he only left after the allegations became public. We already know that the Sens organization knew about the online harassment/bullying early on and since a GM would likely have regular talks with his Captain it's not a leap to assume that he knew whom the Karlssons were suspecting. If he took it seriously he would have talked to other players for their input, including Hoffman. He should have had this settled a lot sooner. Since he didn't, there's a good chance he either didn't believe Karlsson or said something to the effect "Are you sure?" Good god, he might have even played the "Maybe Meinda is not thinking clearly because of what she went through". And maybe some of that is even true but the fact remains -- they knew and did not do anything until it came out.
And then there's the Randy Lee situation, the Melnyk situation*s*.